| | | | | Major bleeding events | |
Matching characteristics | |
Ischemic stroke | ICH | Other major bleeds | | | Event N = 7,799 | Control N = 33,084 | Event N = 1,276 | Control N = 5,097 | Events N = 14,996 | Control N = 60,058 |
| | CHA2DS2-VASc score | | | | | | | | Mean (SD) | 3.89 (1.49) | 3.81 (1.46) | 3.72 (1.46) | 3.68 (1.50) | 3.91 (1.51) | 3.69 (1.46) | | Median (range) | 4 (0–9) | 4 (0–9) | 4 (1–9) | 4 (0–9) | 4 (0–9) | 4 (0–9) | | CHA2DS2-VASc, categorized, n (%) | | | | | | | | 0 points | 7 (0.1%) | 17 (0.1%) | 0 (0.0%) | 3 (0.1%) | 13 (0.1%) | 30 (0.1%) | | 1-2 points | 1,353 (17.4%) | 6,107 (18.5%) | 272 (21.3%) | 1,149 (22.5%) | 2,647 (17.7%) | 12,949 (21.6%) | | 3–5 points | 5,337 (68.4%) | 22,861 (69.1%) | 858 (67.2%) | 3,358 (65.9%) | 10,086 (67.3%) | 40,401 (67.3%) | | 6–9 points | 1,102 (14.1%) | 4,096 (12.4%) | 146 (11.4%) | 587 (11.5%) | 2,249 (15.0%) | 6,678 (11.1%) | | HAS-BLED score | | | | | | | | Mean (SD) | 1.33 (0.75) | 1.30 (0.75) | 1.32 (0.76) | 1.27 (0.77) | 1.33 (0.78) | 1.25 (0.76) | | Median (range) | 1 (0–4) | 1 (0–4) | 1 (0–3) | 1 (0–3) | 1 (0–4) | 1 (0–4) | | HAS-BLED, categorized, n (%) | | | | | | | | 0 points | 1,036 (13.3%) | 4,552 (13.8%) | 181 (14.2%) | 790 (15.5%) | 2,099 (14.0%) | 9,777 (16.3%) | | 1-2 points | 6,481 (83.1%) | 27,370 (82.7%) | 1,042 (81.7%) | 4,105 (80.5%) | 12,139 (81.0%) | 48,293 (80.4%) | | 3–5 points | 282 (3.6%) | 1,165 (3.5%) | 53 (4.2%) | 202 (4.0%) | 757 (5.1%) | 1,994 (3.3%) |
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