Pathophysiological Implications of Different Bicuspid Aortic Valve Configurations

Table 1

Cusp fusion pattern—local hemodynamics—qualitative severity of aortic media disease.

Different local aortic MMP and TIMP patterns in different types of BAV [12]
Presence of BAV correlates with circulating MMP and TIMP levels [13]
Majority type S1-RL BAV linked to more severe media disease [14]