Metabolic Syndrome Derived from Principal Component Analysis and Incident Cardiovascular Events: The Multi Ethnic Study of Atherosclerosis (MESA) and Health, Aging, and Body Composition (Health ABC)

Table 3

Cox proportional Hazard models illustrating the association of MetS-PC per change in one SD with CVD events in the MESA cohort after 5.5 years of follow up overall and by race/ethnicity.

	HR	95% CI	𝑃 value
Model 1
Overall	1.56	1.42, 1.72	0.0001
Caucasian	1.59	1.37, 1.84	0.0001
Chinese	1.42	0.99, 2.01	0.06
African	1.46	1.21, 1.75	0.0001
Hispanic	1.84	1.48, 2.30	0.0001
Model 2
Overall	1.65	1.49, 1.82	0.0001
Caucasian	1.61	1.38, 1.87	0.0001
Chinese	1.49	1.03, 2.15	0.04
African	1.61	1.34, 1.92	0.0001
Hispanic	1.92	1.54, 2.40	0.0001
Model 3
Overall	1.71	1.54, 1.90	0.0001
Caucasian	1.64	1.39, 1.94	0.0001
Chinese	1.59	1.08, 2.35	0.02
African	1.67	1.37, 2.02	0.0001
Hispanic	2.10	1.66, 2.65	0.0001

Standardized MetS-PC; mean (SD), −0.00056 (1); model 1, univariate analysis; model 2, adjusted for age and gender; model 3, model 2, plus cigarette smoking and low-density lipoprotein; the overall hazards were further adjusted for race/ethnicity in models 2 and 3.