Clinical Study

Brachial-Ankle Pulse Wave Velocity Is the Only Index of Arterial Stiffness That Correlates with a Mitral Valve Indices of Diastolic Dysfunction, but No Index Correlates with Left Atrial Size

Table 1

Clinical characteristics of the study population.

Number of subjects41

Age (years)68 ± 11
Gender (% men)66
BMI (kg/m2)26.7 ± 3.6
BSA (m2)1.84 ± 0.22

Hypertension (%)73.2
Dyslipidemia (%)48.8
Diabetes (%)12.2
CAD (%)22.0

Medications
β-blockers (%)34.1
 ACEIs (%)36.6
 ARBs (%)7.3
 CCBs (%)24.4
 Statins (%)43.9
 Aspirin (%)53.7
 Antiplatelets (%)14.6
 Diuretics (%)19.5

Heart rate (bpm)67.3 ± 12.8
SBP (mm Hg)138.5 ± 18.1
DBP (mm Hg)78.8 ± 8.4
PP (mm Hg)59.7 ± 14.2

baPWV (cm/s)1814 ± 415
cfPWV (cm/s)1610 ± 500
AIx (%)20.0 ± 18.3
ABI1.14 ± 0.12

LAD (mm)36.8 ± 6.5
LAVI (ml/m2)33.5 ± 11.7
E (cm/s)79.6 ± 26.0
A (cm/s)76.0 ± 25.5
E/A 1.15 ± 0.54
Age < 60: 1.3 ± 0.4
Age ≥ 60: 1.1 ± 0.6
LVEF (%)63.3 ± 5.0
LVM (g)151.2 ± 36.6
LVMI (g/m2)80.3 ± 21.0
LVDD (mm)45.0 ± 5.1
LVSD (mm)28.4 ± 5.5
IVST (mm)10.0 ± 1.4
PWT (mm)9.7 ± 1.2

BMI: body mass index, BSA: body surface index, CAD: coronary artery disease, ACEIs: angiotensin-converting enzyme inhibitors, ARBs: angiotensin II receptor antagonists, CCBs: calcium channel blockers, SBP: systolic blood pressure, DBP: diastolic blood pressure, PP: pulse pressure, ABI: ankle-brachial index, Aix: augmentation index, cfPWV: carotid-femoral pulse wave velocity, baPWV: brachial-ankle pulse wave velocity, LAD: left atrial diameter, LAVI: left atrial volume index, E: peak early diastolic filling velocity, A: peak late diastolic filling velocity, E/A: E/A ratio; LVEF: left ventricular ejection fraction, LVM: left ventricular mass, LVMI: left ventricular mass index, LVDD: left ventricular end-diastolic diameter, LVSD: left ventricular end-systolic diameter, IVS: interventricular septal end-diastolic thickness, and PWT: posterior wall end-diastolic thickness.