Neutralization by Insulin of the Hypertensive Effect of Dermcidin Isoform 2: An Environmentally Induced Diabetogenic and Hypertensive Protein
Figure 4
Immunoblot analysis of the plasma dermcidin level in hypertensive subjects before and after the ingestion of aspirin. The plasma from hypertensive persons before and after the ingestion (150 mg/70 kg) of aspirin was subjected to immunoblot analysis using dermcidin antibody as described in Section 2. The intensities of the bands obtained were determined using Image J software. Panel (a): 1 represents dermcidin band before the ingestion of aspirin, 2 represents dermcidin band after the oral ingestion of the compound. Panel (b): 3 represents corresponding profile plot of the intensity of the dermcidin band in the hypertensive patients before the ingestion of aspirin, 4 represents the corresponding intensity of the dermcidin band after the ingestion of the compound in the same patients. The figure is a typical representative of at least 10 different experiments using 10 different samples from 10 different volunteers (male = 5, female = 5).
