Leptin Receptor Gene Gln223Arg Polymorphism Is Not Associated with Hypertension: A Preliminary Population-Based Cross-Sectional Study

Table 3

Multivariate Poisson regression model (prevalence ratio and 95% CI) for hypertension, Montes Claros, Brazil, 2013.

Models	PR	95% CI	𝑃 value
Model 1
Genotype GG*	1	—	—
Genotype AG	0.98	0.68–1.43	0.954
Genotype AA	1.07	0.73–1.55	0.712
Model 2 (adjust: age)
Genotype AG	1.02	0.75–1.38	0.887
Genotype AA	0.98	0.72–1.33	0.919
Model 3 (adjust: age and sex)
Genotype AG	1.00	0.75–1.38	0.895
Genotype AA	0.97	0.72–1.32	0.891
Model 4 (adjust: age, sex, and education)
Genotype AG	1.02	0.75–1.39	0.868
Genotype AA	0.97	0.72–1.32	0.881
Model 5 (adjust: age, sex, education, and smoke)
Genotype AG	1.04	0.75–1.43	0.801
Genotype AA	0.98	0.72–1.35	0.941
Model 6 (adjust: age, sex, education, smoke, and alcohol intake)
Genotype AG	1.04	0.75–1.42	0.808
Genotype AA	0.98	0.72–1.35	0.938
Model 7 (adjust: age, sex, education, smoke, alcohol intake, and WC)
Genotype AG	1.03	0.75–1.43	0.808
Genotype AA	0.99	0.72–1.35	0.938
Model 8 (adjust: age, sex, education, smoke, alcohol intake, WC, and parental obesity history)
Genotype AG	1.02	0.75–1.38	0.862
Genotype AA	0.95	0.70–1.27	0.748

∗GG genotype as reference group. WC: waist circumference.