Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease Modeling

Figure 2

Genome editing in cardiovascular disease modeling with induced pluripotent stem cells. Patient-specific induced pluripotent stem cells are corrected using genome editing tools to create a panel of isogenic iPSC lines that are differentiated into cardiomyocytes for disease modeling, drug discovery and screening, and cell therapy.