Assessment of the Protective Role of Prenatal Zinc versus Insulin Supplementation on Fetal Cardiac Damage Induced by Maternal Diabetes in Rat Using Caspase-3 and KI67 Immunohistochemical Stains

Table 6

Percentage frequency distribution of proliferation index in KI67 immunohistochemical stained myocardial sections in the different groups.

Parameter	Group
	C	STZ-DM	STZ-DM + Zn	STZ-DM + In
Low proliferation KI67 index ≤ 15%	12	68	23	27
Intermediate proliferation KI67 index 16–30%	25	17	47	46
High proliferation KI67 index >30%	63	15	30	27
Total (%)	100	100	100	100

Chi-square 113.17.
value < 0.00001.
C: control group, STZ-DM: streptozotocin-induced diabetic group, STZ-DM + In: streptozotocin-induced diabetic treated with insulin group, and STZ-DM + Zn: streptozotocin-induced diabetic treated with Zn group.
, compared to the control group and compared to the STZ-DM group.