Renal Insufficiency and Early Bystander CPR Predict In-Hospital Outcomes in Cardiac Arrest Patients Undergoing Mild Therapeutic Hypothermia and Cardiac Catheterization: Return of Spontaneous Circulation, Cooling, and Catheterization Registry (ROSCCC Registry)
Table 1
Baseline clinical characteristics, prehospital arrest data, and cooling protocol of total population ().
Clinical characteristics
MTH + C ()
MTH + NC ()
value
Age (yrs)
61 ± 12
61 ± 16
1.00
Sex (M)
52 (79)
77 (70)
0.22
Medical history
Diabetes (%)
12 (18)
34 (31)
0.06
Smoking (%)
36 (55)
49 (45)
0.22
Hypertension (%)
36 (55)
65 (59)
0.63
Dyslipidemia (%)
27 (41)
39 (35)
0.42
Prior MI (%)
22 (33)
32 (29)
0.32
Prior PCI (%)
5 (8)
7 (6)
0.63
Baseline CRI (%)
17 (26)
12 (11)
0.24
Cardiac arrest
OHCA (%)
50 (76)
89 (81)
0.44
Witnessed OHCA (%)
61 (92)
83 (75)
0.07
Immediate bystander CPR (%)
36 (55)
40 (45)
0.20
Duration of bystander CPR (min)
6.4 ± 4.1
7.5 ± 4.0
0.08
Time to ROSC from collapse (min)
28.0 ± 14.6
24.0 ± 14.8
0.10
Time from collapse to EMS (min)
8.0 ± 5.0
12.0 ± 12.0
<0.05
Total cooled time (min)
1671 ± 410
1625 ± 551
0.62
Initial arrest rhythm
VF/pulseless VT
61 (92)
39 (35)
<0.05
PEA
5 (8)
61 (65)
<0.05
STEMI
45 (68)
0 (0)
<0.05
Mild therapeutic hypothermia
Time from ROSC to cooling (min)
277 ± 110
211 ± 146
<0.05
Time to achieve 32–34°C from cooling (min)
252 ± 174
312 ± 466
0.30
Total cooled time (min)
1671 ± 410
1625 ± 551
0.56
Values are mean ± SD or (%). MTH + C, mild therapeutic hypothermia with cardiac catheterization; OHCA, out of hospital cardiac arrest; MTH + NC, mild therapeutic hypothermia with no cardiac catheterization; yrs, years; m, males; MI, myocardial infarction; PCI, percutaneous coronary intervention; CRI, chronic renal insufficiency; CPR, cardiopulmonary resuscitation; min, minutes; ROSC, return of spontaneous circulation; EMS, emergency medical services; VF, ventricular fibrillation; VT, ventricular tachycardia; PEA, pulseless electrical activity; STEMI, ST elevation myocardial infarction.
