The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics

Table 1

Phenotype metabolising classes based on CYP2C19 genotype.

Phenotype	Examples of the genotype	Enzyme activity
Ultrarapid metabolizer (UM)	1/17	Normal or increased enzyme activity
	17/17
Extensive metabolizer (EM)	1/1	Normal enzyme activity
Intermediate metabolizer (IM)	1/2	Intermediate enzyme activity
	1/3
	2/17
Poor metabolizer (PM)	2/2	Low or absent enzyme activity
	3/3
	2/3

This table is adapted and modified with permission from the publisher. Original source: Scott et al. (2013) [10]. Copyright© (2013). Published by Wiley. All rights reserved.