Thymoquinone Ameliorates Doxorubicin-Induced Cardiotoxicity in Swiss Albino Mice by Modulating Oxidative Damage and Cellular Inflammation

Table 1

The effect of thymoquinone on serum marker enzymes in doxorubicin-mediated cardiotoxicity in the mice.

Enzymes	Mean ± SD
	Group A (control)	Group B (DOX)	Group C (DOX + TQ10)	Group D (DOX + TQ-20)	Group E (TQ-20)
AST (IU/ml)	68.43 ± 3.53	246.51 ± 6.63	101.45 ± 3.83	77.89 ± 4.47	72.29 ± 5.82
ALT (IU/ml)	45.34 ± 2.60	102.29 ± 5.63	71.43 ± 7.32	57.38 ± 1.86	41.46 ± 4.13
LDH (IU/L)	542.74 ± 5.87	3430.57 ± 1.80	2101.56 ± 7.89	1346.41 ± 4.31	631.1 ± 7.08
CKMB (IU/L)	793.21 ± 5.94	4277.43 ± 8.32	2818.48 ± 8.39	1904.97 ± 4.63	840.17 ± 9.46

Each value is the mean of six replicates with standard deviation; , , and were significant when compared to normal control Group A and toxic control Group B by performing Tukey–Kramer test (posttest).