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Study | Country | Sample size | Mean age (SD) | Intervention (sample size) | Comparison | Mean follow-up time | Outcomes assessed |
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Pérez-Castellano et al. [13] | Spain | 50 | CB = 58 (45, 62) IRF = 56 (40, 61) | Irrigated radiofrequency energy () | Cryoballoon () | 12 months | (i) Freedom from atrial fibrillation, ablation time, procedure time, fluoroscopy time, complications |
Herrera Siklódy et al. [15] | France | 60 | CB = 57 (8) IRF = 56 (10) | Irrigated radiofrequency energy () | Cryoballoon () | 12 months | (i) Freedom from atrial fibrillation, procedure time, fluoroscopy time, complications, biochemical response |
Pokushalov et al. [14] | Russia | 80 | CB = 56 (9) IRF = 56 (11) | Irrigated radiofrequency energy () | Cryoballoon () | 12 months | (i) Freedom from atrial fibrillation, procedure time, fluoroscopy time, complications |
Hunter et al. [16] | United Kingdom | 234 | CB = 56 (11) IRF = 61 (12) Combined = 58 (12) | Irrigated radiofrequency energy () Combined () | Cryoballoon () | 12 months | (i) Freedom from atrial fibrillation, procedure time, fluoroscopy time, complications |
Schmidt et al. [17] | Germany | 99 | CB = 66 (10) IRF = 63 (10) LB = 65 (8) | Irrigated radiofrequency energy () Laser balloon () | Cryoballoon () | Postoperative | (i) Asymptomatic cerebral lesions procedure time |
Kuck et al. [6] | Germany | 750 | CB = 59.9 (9.8) IRF = 60.1 (9.2) | Irrigated radiofrequency energy () | Cryoballoon () | 1.5 years | (i) Recurrence of atrial fibrillation, procedure time, fluoroscopy time, complications |
Luik et al. [5] | Germany | 215 | CB = 61 (54, 66) IRF = 60 (54, 67) | Irrigated radiofrequency energy () | Cryoballoon () | 12 months | (i) Freedom from atrial fibrillation, complications |
Malmborg et al. [18] | Sweden | 110 | CB = 59 (9) PDRF = 62 (7) | Phased duty-cycled radiofrequency energy () | Cryoballoon () | 12 months | (i) Freedom from atrial fibrillation, ablation time, procedure time, fluoroscopy time, complications, quality of life |
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