Prognostic Value of SYNTAX Score II in Patients with Acute Coronary Syndromes Referred for Invasive Management: A Subanalysis from the SPUM and COMFORTABLE AMI Cohorts
Table 1
Baseline characteristics and risk factors.
Variables
SxSIILow ≤21.5
SxSIIMid 21.5–30.6
SxSIIHigh ≥30.6
value
Age
52.3 ± 7.4
60.5 ± 9.5
71.7 ± 10.2
N/A
Gender (male)
239 (97.6)
205 (83.7)
146 (59.8)
N/A
ACS
0.001
STEMI
167 (68.2)
181 (73.9)
189 (77.5)
NSTE-ACS
65 (26.5)
63 (25.7.4)
53 (21.7)
Unstable angina
13 (5.3)
1 (0.4)
2 (0.8)
Hypertension
100 (43.1)
122 (51.7)
155 (68)
<0.001
History of dyslipidemia
143 (61.9)
140 (59.6)
138 (60.8)
0.878
Diabetes mellitus
28 (12.1)
41 (17.4)
39 (17.1)
0.207
History of smoking
207 (84.5)
188 (76.7)
142 (59.2)
<0.001
History of CAD
72 (31.9)
57 (24.2)
38 (17.5)
0.002
Prior MI
11 (4.7)
20 (8.5)
25 (11)
0.049
Prior PCI
19 (8.2)
25 (10.5)
28 (12.3)
0.347
History of PVD
0 (0)
1 (0.4)
23 (9.4)
N/A
History of COPD
3 (1.2)
6 (2.4)
15 (6.1)
N/A
Killip score ≥2
21 (8.5)
31 (12.7)
46 (18.9)
0.003
Prehospital resuscitation
16 (6.5)
8 (3.3)
10 (4.1)
0.226
Vasopressors
5 (2)
4 (1.6)
15 (6.1)
0.007
IABP
3 (1.2)
9 (3.7)
33 (13.5)
<0.001
BMI (kg/m2)
27.7 ± 3.9
27.5 ± 4.2
25.6 ± 3.6
<0.001
HsTnT (ug/l)
0.14 (0.04/0.51)
0.18 (0.04/0.67)
0.24 (0.08/0.73)
0.008
CK-MB (U/l)
24.3 (11/57)
28.5 (12/68)
34 (14/66)
0.104
NT-proBNP (ng/l)
137 (47/311)
256 (95/701)
586 (195/1960)
<0.001
eGFR (ml/min/1.73 m2)
127.8 ± 30.8
106.9 ± 33.6
69.5 ± 29.4
N/A
Fasting glucose (mmol/l)
6.8 ± 2.2
7.4 ± 2.9
7.8 ± 3.4
0.001
LVEF (%)
55.7 ± 7.4
50.7 ± 10.2
45.9 ± 12.4
N/A
Depicted are counts, n incidence (%) or mean ± SD or median (25/75) percentile. Variables are included in the score; value reported as N/A. CAD, coronary artery disease; MI, myocardial infarction; PCI, percutaneous coronary intervention; PVD, peripheral vascular disease; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction.
