Research Article

Prognostic Value of SYNTAX Score II in Patients with Acute Coronary Syndromes Referred for Invasive Management: A Subanalysis from the SPUM and COMFORTABLE AMI Cohorts

Table 4

Clinical outcomes at 1 year stratified by tertiles of SYNTAX score II.

Outcomes at one yearSxSIILow≤21.5SxSIIMid 21.5–30.6SxSIIHigh ≥30.6 value

All-cause mortality2 (0.8)3 (1.2)23 (9.4)<0.00128 (3.8)
Cardiovascular death1 (0.4)3 (1.2)17 (7.0)<0.00121 (2.8)
Noncardiovascular death1 (0.4)0 (0.0)6 (2.4)0.0077 (0.9)
Cerebrovascular event0 (0.0)1 (0.4)3 (1.2)0.1344 (0.5)
Myocardial infarction1 (0.4)9 (3.7)10 (4.1)0.01120 (2.7)
Clinically driven revascularization4 (1.6)16 (6.5)21 (8.6)0.00241 (5.6)
Target vessel revascularization2 (1.7)13(5.3)13 (5.3)0.01128 (3.8)
Any revascularization4 (1.6)18(7.3)21 (8.6)0.00243 (5.8)
Restenotic lesion revascularisation3 (1.7%)2 (1.2%)9 (1.8%)0.0314 (1.9)
Any stent thrombosis2 (1.1%)0 (0%)3 (1.9%)0.595 (0.6)
 Early thrombosis1 (0.6%)0 (0%)2 (1.3%)0.503 (0.4)
 Late thrombosis1 (0.6%)0 (0%)1 (0.6%)0.772 (0.2)
MACE5 (2.0)20 (8.2)35 (14.3)<0.00160 (7.4)
MACCE6 (2.4)21 (8.6)43 (17.6)<0.00170(9.5)

MACE, major adverse cardiac events; MACCE, major adverse cardiac and cerebrovascular events.