Novel Models for the Prediction of Left Atrial Appendage Thrombus in Patients with Chronic Nonvalvular Atrial Fibrillation
Table 3
Diagnostic value of LA echocardiographic parameters for LAAT prediction.
LA parameter
Cutoff value
Sensitivity (%)
Specificity (%)
AUC
95% CI
value
Area in four-chamber view (cm2)
>26.7
74.3
63.3
0.71
0.63–0.78
<0.001
Area in two-chamber view (cm2)
>26.8
71.4
75.2
0.76
0.68–0.83
<0.001
Diameter (cm)
>5.7
94.3
32.1
0.65
0.57–0.73
<0.001
Volume (mL)
>99.8
68.6
73.4
0.73
0.65–0.80
<0.001
Volume index (mL/m2)
>57.0
77.1
64.2
0.72
0.64–0.79
<0.001
Positive strain in two-chamber view (%)
≤7.81
91.4
67.0
0.81
0.74–0.87
<0.001
Positive strain in four-chamber view (%)
≤6.7
77.1
77.1
0.84
0.76–0.89
<0.001
Positive strain rate in two-chamber view (s−1)
≤0.58
74.3
60.6
0.71
0.63–0.78
<0.001
Positive strain rate in four-chamber view (s−1)
≤0.55
65.7
72.5
0.75
0.67–0.82
<0.001
Negative strain rate in two-chamber view (s−1)
>−0.94
100
44.0
0.71
0.63–0.78
<0.001
Negative strain rate in four-chamber view (s−1)
>−0.73
85.7
70.6
0.83
0.76–0.89
<0.001
Data were obtained using receiver operating characteristic curve analysis. 95% CI: 95% confidence interval; AUC: area under the curve; LA: left atrial; LAAT: left atrial appendage thrombus.
