Research Article

Echocardiographic Findings in Patients with Atrial Septal Aneurysm: A Prospective Case-Control Study

Table 1

Baseline demographics, echocardiographic parameters, and pathologies of the study population.

VariableAtrial septal aneurysm value
No ()Yes ()

Age (years)49 ± 1549 ± 150.86
Women (n)242 (64.2%)242 (64.2%)1.00
Hypertension (n)113 (29.9%)116 (30.7%)0.81
Diabetes mellitus (n)46 (12.2%)44 (11.6%)0.82
Current smoker (n)66 (17.5%)56 (14.8%)0.37
Coronary artery disease (n)64 (16.9%)71 (18.8%)0.50
Ischemic stroke (n)3 (0.8%)14 (3.7%)<0.001
Hyperlipidemia (n)60 (15.9%)64 (16.9%)0.69
Left atrium anterior-posterior dimension (mm)37.0 ± 4.836.9 ± 4.80.64
Left ventricle end diastolic diameter (mm)45.6 ± 3.845.7 ± 3.90.70
Left ventricle end systolic diameter (mm)28.4 ± 2.928.5 ± 2.80.60
Aortic root diameter (mm)28.6 ± 3.129.2 ± 3.90.05
Ascending aorta diameter (mm)41.5±0.244±0.30.02
Ejection fraction (%)67.4 ± 2.567.1 ± 3.00.08
Aortic valve regurgitation (n)42 (11.1%)61 (16.1%)0.04
Mild36 (85.7%)50 (82.0%)
Moderate6 (14.3%)10 (16.4%)
Severe0 (0%)1 (1.6%)
Mitral valve regurgitation (n)93 (24.6%)148 (39.2%)<0.001
Mild89 (95.7%)145 (98.0%)
Moderate4 (4.3%)2 (1.35%)
Severe0 (0%)1 (0.67%)
Ascending aortic aneurysm6 (1.5%)17 (4.5%)<0.001
Mitral valve prolapse2 (0.5%)3 (0.7%)0.72
Patent foramen ovale (n)2 (0.5%)23 (6.1%)<0.001
Atrial septal defect (n)1 (0.2%)9 (2.3%)0.01
Ventricular septal defect (n)1 (0.2%)1 (0.2%)1.00