Endogenous Bufadienolides, Fibrosis and Preeclampsia

<div>Scheme of the Fli-1-dependent profibrotic pathway activated via binding of marinobufagenin (MBG) to Na/K-ATPase (NKA). The interaction of MBG with NKA leads to activation/phosphorylation of Src followed by activation/phosphorylation PLC and PKC via scaffolding function of NKA.</div>

Cardiology Research and Practice

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Figure 2

Figure 2: Endogenous Bufadienolides, Fibrosis and Preeclampsia 