Acute coronary syndrome (ACS) is a leading cause for hospital admissions both in Europe and the United States resulting in high medical care expenses. During the past 25 years, there have been important advances in the therapeutic options for ACS patients with improved medical therapy and the introduction of percutaneous coronary intervention. However, despite the reduction of morbidity and mortality due to various refinements in medical treatment and technology, there are still opportunities to improve outcome in the first months after the event and on the longer run. Accurate recognition of patients that can benefit from additional therapies is therefore crucial. The standard of care of patients with ACS includes a stepwise approach including different imaging modalities to make a final diagnosis, with rest echocardiography as the most common of the techniques. Recently, new imaging techniques have emerged resulting in a wide array of choices available to cardiologists to improve clinical decision making. These new modalities can be helpful in several aspects including the detection and differential diagnosis of ACS, guiding clinical decision making, and improving risk stratification after an event. This is an exciting and a rapidly expanding field of investigation.

In this context, we invite authors to present original research that will stimulate the continuing efforts in defining the role of cardiac imaging in patients with ACS. Especially, reviews and/or meta-analyses that summarize the recent advances of different imaging technique in ACS patients are of interest. The special issue will become an international forum for researchers to summarize the most recent development and ideas in this field. Potential topics include, but are not limited to:

• Pathophysiology of ACS and imaging
• The role of different imaging techniques for timely and accurate identification of ACS patients
• Comparison of imaging techniques in the diagnosis and/or exclusion of ACS
• The role of cardiac imaging for improving risk stratification in ACS patients
• The role of different imaging techniques to identify prognostic markers of left ventricular remodeling, such as the area at risk, extent of infarction, or no-reflow
• Imaging-guided therapy in patients with ACS
• Diagnostic imaging of patients with ACS and chronic total occlusion
• The role of molecular imaging in patients with ACS and its relation to atherosclerotic inflammation
• The current status of vulnerable plaque detection and the underlying mechanisms
• New imaging technologies to improve current procedures

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