Targeted Disruption of Calcium/NFAT Signaling Reveals a Left-Right Determination Disorder in the Pharyngeal Arch Artery

Table 2

Appearance of right aortic arch after infusion of FK506 into amniotic fluid.

Days of infusion of FK506	% of right aortic arch + right ductus arteriosus
E7.5
0.8 mg/kg	23 (5/22)
0.08 mg/kg	0 (0/18)
Saline	0 (0/28)
E8.5
3.0 mg/kg	0 (0/4)
1.5 mg/kg	33 (10/30)
0.8 mg/kg	28 (9/32)
Saline	0 (0/30)
E10.5
0.8 mg/kg	0 (0/16)