Effects of Calcium-Channel Noise on Dynamics of Excitation-Contraction Coupling in Paced Cardiac Cells

Figure 2

Plots of peak calcium 𝑐^𝑝 versus APD for the coupled system (10), with the same function 𝑔 in Figure 1, and 𝑓(𝐷_𝑛)=0.2[1−1/(1+𝑒^{(𝐷𝑛−0.02)/0.04})]+0.1𝑒^{−(𝐷𝑛−0.06)2/0.8}, and  𝑞(𝐷_𝑛)=1−0.5𝑒^{−𝐷𝑛/0.02} at the parameters 𝑇=0.4,𝛼=2,𝑤=0.4, and 𝑐_𝑡=2. (a) 𝜖=0, and 𝛾=−0.02. (b) 𝜖=0.5, under the other conditions same as in (a). (c) 𝜖=0 and 𝛾=0.02. (d) 𝜖=0.5, under the other conditions same as in (c).

(a)

(b)

(c)

(d)