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Disease Markers
Volume 33 (2012), Issue 1, Pages 1-10
http://dx.doi.org/10.3233/DMA-2012-0904
Review

Cancer Biomarker Discovery: Lectin-Based Strategies Targeting Glycoproteins

David Clark and Li Mao

Department of Oncology and Diagnostic Sciences, University of Maryland, School of Dentistry, Baltimore, MD, USA

Received 21 May 2012; Accepted 21 May 2012

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Biomarker discovery can identify molecular markers in various cancers that can be used for detection, screening, diagnosis, and monitoring of disease progression. Lectin-affinity is a technique that can be used for the enrichment of glycoproteins from a complex sample, facilitating the discovery of novel cancer biomarkers associated with a disease state.