Nuclear p27 Expression Confers a Favorable Outcome for Nasopharyngeal Carcinoma Patients

Table 2

Summary of univariate and multivariate Cox regression analysis of overall survival duration.

Parameter	Univariate analysis			Multivariate analysis
	𝑃	HR	95% CI	𝑃	HR	95% CI
Gender
Male versus female	0.485	0.488	0.665–2.361
Age
≥50 versus <50 years	0.787	0.073	0.620–1.881
Family tumor history
Yes versus no	0.349	0.877	0.000–28.401
Smoking
Yes versus no	0.387	0748	0.368–1.474
Chemotherapy
Yes versus no	0.700	1.153	0.560–2.372
Radiotherapy
Yes versus no	0.005	0.369	0.184–0.742	0.990	0.994	0.419–2.358
T classification
T1-T2 versus T3-T4	0.000	28.042	2.674–8.496	0.014	2.725	1.222–6.075
N classification
N0-N1 versus N2-N3	0.000	2.950	1.662–5.237	0.240	1.633	0.720–3.702
M classification
M0 versus M1	0.000	35.042	5.031–24.906	0.005	4.461	1576–12.633
TNM clinical stage
I-II versus III-IV	0.000	19.386	3.592–27.943	0.051	3.758	0.992–14.239
p27 nuclear expression
Positive expression versus negative expression	0.009	0.460	0.257–0.822	0.690	0.878	0.464–1.661