Clinical Study
Asymmetric and Symmetric Dimethylarginine in Adolescents with Hyperuricemia
Table 1
Clinical and biochemical characteristics of patients and the reference group.
| | Variables | Patients | Controls | | | Median (Q1–Q3) |
| | Age (years) | 16.15 (14–17) | 15.8 (10.8–17.1) | NS | | BMI (Z-score) | 1.08 (−0.36–1.64) | 0.2 (−0.2–0.8) | <0.01 | | Serum creatinine (mg/dL) | 0.74 (0.57–0.86) | 0.57 (0.43–0.71) | <0.01 | | Serum urea (mg/dL) | 26 (23–30) | 22.5 (20–27) | <0.05 | | Serum uric acid (UA) (mg/dL) | 6.5 (5.83–7.13) | 4.06 (3.3–4.7) | <0.01 | | eGFR (mL/min./1.73 m2) | 99.76 (88.41–121.45) | 117.72 (111.43–144.05) | <0.01 | | Fasting plasma glucose (FPG) (mg/dL) | 91.5 (87–95) | 91 (88–93) | NS | | Triglycerides (TG) (mg/dL) | 93 (76–138) | 85 (61–117) | NS | | Total cholesterol (mg/dL) | 162 (145–187) | 142 (136–166) | <0.05 | | HDL (mg/dL) | 52.36 (42.00–57.00) | 55.00 (52.36–56.00) | NS | | LDL (mg/dL) | 90.66 (73.00–104.00) | 90.00 (78–90.66) | NS | | ADMA (μmol/L) | 0.47 (0.41–0.53) | 0.46 (0.83–0.49) | NS | | SDMA (μmol/L) | 0.54 (0.44–0.63) | 0.51 (0.39–0.53) | <0.01 | hs-CRP (mg/L)
| 0.74 (0.17–3.52) | 0.17 (0.13–1.54) | <0.01 | Albuminuria (mg/24 h)
| 4.55 (2.72–9.9) | 5.95 (0.28–100.8) | NS | | SBP (mmHg) | | | | | D | 136 (130–140) | 118 (111–124) | <0.01 | | N | 120 (115–124) | 110 (105–112) | <0.01 | | DBP (mmHg) | | | | | D | 73 (69–78) | 67 (64–70) | <0.01 | | N | 64 (60–67) | 57.5 (54–59) | <0.01 |
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