COMT-Val158Met-Polymorphism Is Not a Risk Factor for Acute Kidney Injury after Cardiac Surgery

Table 1

Demographics.

	Val/Val; 417 (24.0%)	Val/Met; 850 (48.8%)	Met/Met; 474 (27.2%)	𝑃
Age (years)	66.33±11.62	66.01±11.67	66.08±12.28	0.901
Male	295 (70.7%)	596 (70.1%)	323 (68.1%)	0.661
Weight (kg)	80.00±14.74	80.16±14.21	78.87±13.11	0.293
Height (cm)	171.54±9.23	171.3±9.3	171.5±8.2	0.871
LVEF*	57.83±14.10	57.79±14.83	58.57±15.11	0.474
PAD**	23 (5.6%)	55 (6.6%)	23 (4.9%)	0.460
COPD***	25 (6.1%)	63 (7.6%)	29 (6.2%)	0.521
Previous cardiac surgery	38 (9.2%)	71 (8.5%)	37 (7.9%)	0.736
PMI****	62 (15.1%)	108 (12.9%)	75 (16.2%)	0.252
Atrial fibrillation	74 (24.3%)	148 (22.9%)	84 (22.9%)	0.789
Cardiovascular risk factors
Arterial hypertension	289 (77.1%)	586 (75.9%)	327 (75.9%)	0.897
Diabetes	79 (24.5%)	156 (18.4%)	97 (24.9%)	0.655
Tobacco smoking habit	88 (21.1%)	157 (18.5%)	77 (16.2%)	0.706
Hyperlipidaemia	125 (37.4%)	267 (38.1%)	149 (38.0%)	0.971
Preoperative medication
Beta-blockers	154 (37.5%)	333 (40.0%)	185 (39.8%)	0.676
Diuretics	154 (37.5%)	324 (38.8%)	184 (39.6%)	0.811
ACE inhibitor*****	101 (24.6%)	225 (27.0%)	145 (31.2%)	0.081
Statins	111 (26.6%)	239 (28.1%)	136 (28.7%)	0.776
Nitrates	20 (4.8%)	37 (4.4%)	27 (5.7%)	0.551
Preoperative laboratory findings
Hemoglobin (g/dL)	13.59±1.56	13.59±1.52	13.64±1.53	0.908
Urea (mg/dL)	45.82±24.78	43.01±22.03	43.17±23.67	0.242
Creatinine (mg/dL)	1.01±0.38	1.0±0.38	0.98±0.31	0.556

∗LVEF: left ventricular ejection fraction.
∗∗PAD: peripheral arterial disease.
∗∗∗COPD: chronic obstructive pulmonary disease.
∗∗∗∗PMI: previous myocardial infarction.
∗∗∗∗∗ACE: angiotensin converting enzyme.