| | Function | Cytokine [references] |
| | Immune suppression | TGF- [13, 16, 37, 60] |
| | Growth regulation | MIF [13, 24, 52, 53] |
| | Transcription regulation | IL-1 [13, 38],
IL-6 [39, 40],
IL-8 [25, 41, 61] |
| Inflammatory
cytokines secretion | IL-1 [11, 13, 38],
IL-6 [11, 13] |
| | Apoptosis negative regulation | FasL [44, 45, 65] |
| Host immune stimulation
(Th1 response) | IL-2 [66],
IFN- [66],
IL-12 [62, 67],
IL-18 [62, 67] |
| | Angiogenesis stimulation | VEGF-A [7, 8, 13, 17–24, 41, 54–56],
VEGF-C [7, 13, 25–35, 56–59],
VEGF-D [13, 36, 59],
IL-8 [13, 24, 41, 61],
HGF [13, 41, 64, 74],
bFGF [7, 9, 13, 46, 47],
PDGF-BB [13, 63],
MIF [13, 24, 52, 53] |
| | Metastasis induction | VEGF-A [8, 9, 13, 17–24, 41, 54–56],
VEGF-C [9, 13, 25–35, 56–59],
VEGF-D [13, 36, 59],
bFGF [13, 46, 47],
HGF [41, 64, 74],
midkine [50, 51, 57] |
|
|
