Brain Hypothermic Therapy Dramatically Decreases Elevated Blood Concentrations of High Mobility Group Box 1 in Neonates with Hypoxic-Ischemic Encephalopathy

<table>HMGB1 changes in cases of the BHT (+) and BHT (−) groups. The Mann-Whitney test was performed. These neonates included 8 with HIE in whom BHT was indicated and 5 controls diagnosed as having HIE but who were not suitable candidates for BHT.</table>

Disease Markers

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Figure 2

Figure 2: Brain Hypothermic Therapy Dramatically Decreases Elevated Blood Concentrations of High Mobility Group Box 1 in Neonates with Hypoxic-Ischemic Encephalopathy 

Figure 2 | Brain Hypothermic Therapy Dramatically Decreases Elevated Blood Concentrations of High Mobility Group Box 1 in Neonates with Hypoxic-Ischemic Encephalopathy 