Combination of Strong MMP-2 and Weak TIMP-2 Immunostainings Is a Significant Prognostic Factor in Endometrial Carcinoma

Table 2

The independent and significant prognostic factors for the cancer-specific survival of endometrial cancer patients as evaluated by the Cox regression method. Relative risk of death, its 95% confidence interval, and 𝑃 values are given for each covariate. 𝑛=225.

Variable	Relative risk of death	𝑃 value to remove
Stage		<0.001
I	1
II	2.24 (0.89–5.65)
III	3.65 (1.65–8.09)
IV	13.30 (3.58–49.30)
Grade		0.003
1	1
2	2.91 (1.23–6.86)
3	4.98 (1.98–12.50)
MMP-2 & TIMP-2		0.073
MMP2− & TIMP2− or +	1
MMP2+ & TIMP2+	2.30 (0.29–18.34)
MMP2+ & TIMP2−	4.70 (0.63–35.00)