A Semiautomated Framework for Integrating Expert Knowledge into Disease Marker Identification

Table 3

The validation results (in CA) on the cluster-based biomarker candidates using a human plasma data set.

Functional group no. in Table 2	CA from mouse plasma-defined clusters in		CA from mouse BALF-defined clusters in
	Mouse plasma	Human plasma	Mouse BALF	Human plasma
1	0.54	0.93	0.79	0.93
2	0.58	0.86	0.93	0.79
3	0.56	0.71	0.72	0.71
4^1	0.83	0.71	0.79	0.79
5	0.63	0.79	0.83	0.64
6	0.53	0.79	0.62	0.64
1, 4	0.80	0.86
2, 5^1			1.00	0.71
1–6	0.83	0.93	0.81	0.86

1The best performing clusters from the indicated mouse data set.