Soluble Lectin-Like Oxidized Low Density Lipoprotein Receptor-1 as a Biochemical Marker for Atherosclerosis-Related Diseases

Table 2

Circulating sLOX-1 levels in coronary artery disease.

Disease condition	Median (range)	P values	Reference
CAD	1-2 vessels: 611 (346–1313) pg/mL; 3-4 vessels: 2143 (824–3201) pg/mL	𝑃<0.05 versus controls; 𝑃<0.001 versus controls; 𝑃<0.05 versus 1-2 vessels	[24]
Healthy subjects	268 (111–767) pg/mL
LAD artery			[25]
(i) proximal/mid lesion; (ii) distal lesion	1.07 ± 0.33 ng/mL; 0.70 ± 0.17 ng/mL	𝑃<0.001
ACS	1.610 (0.941–2.264) ng/mL	𝑃<0.01 versus stable CAD	[14]
Stable CAD	0.579 (0.265–1.172) ng/mL
Stable CAD	Simple lesion: 0.426 (0.195–1.075) ng/mL; Complex lesion: 0.914 (0.489–1.296) ng/mL	𝑃<0.01 versus simple lesion
Stable CAD + PCI	MI: 167 ± 89 pg/mL; Non-MI: 99 ± 68 pg/mL	𝑃<0.001	[27]
Stable CAD + PCI	ISR		[28]
	Baseline 0.39 (0.27–0.54) ng/mL
	After PCI 0.85 (0.63–0.98) ng/mL	𝑃<0.01 versus baseline and non-ISR
	Non-ISR
	Baseline 0.32 (0.28–0.62) ng/mL
	After PCI 0.45 (0.36–0.84) ng/mL	𝑃<0.01 versus baseline

LAD: left anterior descending; ACS: acute coronary syndrome; CAD: coronary artery disease; PCI: percutaneous coronary intervention; MI: myocardial infarction; ISR: in-stent restenosis.