Research Article
Association between Angiotensin II Type 1 Receptor Polymorphism and Sudden Cardiac Death in Myocardial Infarction
Table 2
Distributions of demographic and relevant clinical risk factors between ACS patients and healthy controls and the estimated OR for each risk factor.
| Subject characteristics | ACS patients () | Controls () | Univariate analysis | P | Multivariate analysis | P | OR (95% CI) | OR (95% CI) |
| AT1R-genotypes | | | | | | | AA | 241 | 316 | 1 (ref.) | | 1 (ref.) | | AC | 329 | 269 | 1.17 (0.79–2.1) | 0.603 | 1.284 (0.595–2.773) | 0.524 | CC | 179 | 42 | 2.76 (1.07–6.49) | 0.004 | 4.295 (1.436–12.851) | 0.009 | Mean age | | | 0.75 (0.24–2.76) | 0.98 | 1.25 (0.46–2.96) | 0.425 | Sex—male | 432 | 354 | 1.53 (0.89–2.62) | 0.123 | — | — | Systolic blood pressure ≥ 140 mmHg | 327 | 97 | 9.73 (3.44–17.16) | <0.001 | 6.97 (2.53–14.37) | 0.003 | Diastolic blood pressure ≥ 90 mmHg | 94 | 23 | 5.92 (1.47–9.81) | 0.002 | 3.65 (1.45–10.40) | 0.004 | Diabetes mellitus | 329 | 0 | 14.22 (4.98–25.26) | <0.001 | 12.75 (3.41–23.58) | 0.001 |
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