Association of Functional VKORC1 Promoter Polymorphism with Occurrence and Clinical Aspects of Ischemic Stroke in a Greek Population

Table 3

VKORC1 −1639G  >  A polymorphism in relation to stroke severity on admission and functional outcome at one month after stroke.

Genotypes	Severe	Moderate	Mild	𝑃^∗	SSS score; mean (SD)	𝑃^∗∗	Poor outcome; (mRS^a≥ 2)	𝑃^∗∗∗
GG/GA	33 (75.0%)	25 (75.8%)	21 (75.0%)	0.99	32.9 (14.8)	0.96	67 (64.4%)	0.31
AA	11 (25.0%)	8 (24.2%)	7 (25.0%)		32.2 (15.2)		18 (52.9%)

amRS: modified Rankin scale.
𝑃^∗ refers to the distribution of VKORC1 genotypes within stroke severity groups (𝜒² test).
𝑃^∗∗ refers to the comparison of mean Scandinavian Stroke Scale (SSS) scores between VKORC1 genotypes (Mann-Whitney test).
𝑃^∗∗∗ refers to the distribution of VKORC1 genotypes within functional outcome groups (𝜒² test).