EphB4 Tyrosine Kinase Stimulation Inhibits Growth of MDA-MB-231 Breast Cancer Cells in a Dose and Time Dependent Manner
Figure 4
(a) Eph receptor stimulation is lost during carcinogenesis due to down-regulation of ephrin ligands. (b) It was shown in our study that representation of exogenous ephrinB2 to re-establish balance between receptor and ligand signaling is able to exhibits anti-tumor effects.
