Evaluation of Molecular Species of Prostate-Specific Antigen Complexed with Immunoglobulin M in Prostate Cancer and Benign Prostatic Hyperplasia
Figure 4
Representative spectra of free PSA isoforms. On-chip ion-exchange chromatography of PCa fPSA (a) and BPH fPSA (b) was performed on anion exchanger, Q10 (A), and cation exchanger, CM10 (B), array at pH 8. The -axis represents the distribution of ions by mass (mass to charge ratio, ) and the -axis gives the signal intensity of the ions. M + 2H: double charged ion. Peaks corresponding to PSA-immunoreactive species are considered as relevant.
