Inflammatory Cytokines and the Risk of Cardiovascular Complications in Type 2 Diabetes

Table 5

Pearson product-moment analysis of correlations between lymphocyte expression of intracellular cytokines and glycemic and lipid parameters in CHD-afflicted T2DM patients.

	HbA1C	HDL	LDL
All T2DM
CD4+IFN-Υ+ T cells	𝑟=−0.097
CD4+IL-8+ T cells		𝑟=−0.037
CD4+IL-17+ T cells		𝑟=0.039
CD4+IL-1β+ T cells
CD4+CD25+FOXP3+/Th17 cells	𝑟=0.188		𝑟=−0.153
T2DM with CHD
CD4+IFN-Υ+ T cells	𝑟=0.975^∗∗
CD4+IL-8+ T cells		𝑟=−0.838^∗
CD4+IL-17+ T cells		𝑟=−0.801^∗
CD4+IL-1β+ T cells			𝑟=0.903^∗
CD4+CD25+FOXP3+/Th17 cells	𝑟=−0.616^∗
T2DM without CHD
CD4+IFN-Υ+ T cells	𝑟=−0.068
CD4+IL-8+ T cells		𝑟=0.053
CD4+IL-17+ T cells		𝑟=−0.064
CD4+IL-1β+ T cells			𝑟=−0.286
CD4+CD25+FOXP3+/Th17 cells	𝑟=0.242
Healthy control
CD4+IFN-Υ+ T cells	𝑟=0.391
CD4+IL-8+ T cells		𝑟=0.531
CD4+IL-17+ T cells		𝑟=0.179
CD4+IL-1β+ T cells			𝑟=0.241
CD4+CD25+FOXP3+/Th17 cells	𝑟=0.237

∗Significant direct or inverse correlation (𝑃<0.05) and **significant direct or inverse correlation (𝑃<0.01).