Research Article
FAS and FASL Gene Polymorphisms Are Not Associated with Hepatitis B Virus Infection Based on a Case-Control Study in a Brazilian Population
Table 2
Comparison of genotype frequencies of the FAS and FASL polymorphisms among the active chronic hepatitis patients and inactive carriers.
| | Genotype profile | Active chronic () n (%) | Inactive carrier () n (%) | Adjusted OR* | 95% CI | P value‡ |
| | FAS-670 A>G | | | | | | | AA | 19 (21.35) | 06 (22.22) | | | | | AG | 41 (46.07) | 14 (51.85) | | | | | GG | 29 (32.58) | 07 (25.93) | | | | | AG + GG | 70 (78.65) | 21 (77.78) | 0.9666 | 0.32–2.89 | 0.8003 | | FAS-1377 G>A | | | | | | | GG | 72 (80.90) | 22 (81.48) | | | | | GA | 15 (16.85) | 05 (18.52) | | | | | AA | 02 (02.25) | 0 (00.00) | | | | | GA + AA | 17 (19.10) | 05 (18.52) | 1.0990 | 0.34–3.54 | 0.6368 | | Ivs2ntFASLG-124 A>G | | | | | | | AA | 78 (87.64) | 22 (81.48) | | | | | AG | 11 (12.36) | 04 (14.82) | | | | | GG | 0 (00.00) | 01 (03.70) | | | | | AG + GG | 11 (12.36) | 05 (18.52) | 0.5348 | 0.16–1.78 | 0.3328 | | Ivs3ntFASLG-169 T>ΔT | | | | | | | TT | 69 (77.53) | 18 (66.67) | | | | | T/ΔT | 17 (19.10) | 08 (29.63) | | | | | ΔT/ΔT | 03 (03.37) | 01 (03.70) | | | | | T/ΔT + ΔT/ΔT | 20 (22.47) | 09 (33.33) | 0.5594 | 0.21–1.49 | 0.5499 | | FASLG-844 C>T | | | | | | | CC | 38 (42.70) | 13 (48.15) | | | | | CT | 39 (43.82) | 08 (29.63) | | | | | TT | 12 (13.48) | 06 (22.22) | | | | | CT + TT | 51 (57.70) | 14 (51.85) | 1.2228 | 0.49–3.03 | 0.3484 |
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Multiple logistic regression; ‡G test.
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