Association between −308 G/A TNF-α Polymorphism and Appendicular Skeletal Muscle Mass Index as a Marker of Sarcopenia in Normal Weight Obese Syndrome

Table 4

Anthropometric and body composition (DXA) parameters in study groups in accordance with G/A −308 TNF-α polymorphism.

Parameters	NW 𝑛. 17			NWO 𝑛. 30			Preobese 𝑛. 48
	All; (𝑛. 17)	Carrier (−); (𝑛. 13)	Carrier (+); (𝑛. 4)	All; (𝑛. 30)	Carrier (−); (𝑛. 22)	Carrier (+); (𝑛. 8)	All; (𝑛. 48)	Carrier (−); (𝑛. 35)	Carrier (+); (𝑛. 13)
Weight (Kg)	52,43 ± 7,33	55,19 ± 12,14	51,95 ± 5,75	58,68 ± 5,07^a	57,86 ± 5,04^d	60,93 ± 4,75^s	80,80 ± 12,78^bc	81,91 ± 13,18^ef	76,60 ± 10,85^hi
BMI (Kg/m^2)	19,61 ± 1,80	20,91 ± 4,38	19,03 ± 1,71	22,88 ± 1,48^a	22,77 ± 1,61^d	23,17 ± 1,07^s	30,88 ± 4,03^bc	30,90 ± 3,98^ef	30,21 ± 3,72^t
WC (cm)	66,03 ± 4,95	67,00 ± 4,89	62,17 ± 3,40	73,97 ± 7,78^a	71,95 ± 4,22^d	79,25 ± 12,14^w	88,01 ± 10,84^bc	88,52 ± 11,01^ef	84,61 ± 9,40^t
HC (cm)	87,10 ± 12,61	86,29 ± 14,10	90,33 ± 0,58	99,29 ± 6,89	97,31 ± 4,31^d	104,50 ± 9,68	110,01 ± 13,33^bc	109,60 ± 14,37^e	109,33 ± 8,90
W/H	0,77 ± 0,14	0,80 ± 0,14	0,69 ± 0,04	0,74 ± 0,04	0,74 ± 0,04	0,76 ± 0,05	0,81 ± 0,10^nc	0,82 ± 0,11^e	0,77 ± 0,07
PBF	24,47 ± 2,95	25,68 ± 6,19	25,43 ± 3,37	35,94 ± 4,79^a	36,05 ± 4,86^d	35,64 ± 4,90^g	46,00 ± 5,21^bc	45,96 ± 5,71^ef	45,65 ± 3,65^hi
TBFat (Kg)	12,77 ± 2,93	14,59 ± 7,57	13.16 ± 3,11	20,98 ± 3,88^a	20,74 ± 3,93^d	21,63 ± 3,93^s	36,57 ± 7,92^bc	36,85 ± 8,19^ef	34,86 ± 6,62^hi
Lean (Kg) arms	3,63 ± 0,75	3,85 ± 0,83	3,27 ± 0,60	3,59 ± 0,38	3,58 ± 0,40	3,62 ± 0,34	4,14 ± 1,04^bc	4,17 ± 1,18^f	4,09 ± 0,66
Lean (Kg) legs	12,40 ± 1,54	12,74 ± 1,81	12,02 ± 0,90	12,10 ± 1,34	11,77 ± 1,15	12,96 ± 1,49	13,90 ± 2,45^nc	14,15 ± 2,77^ef	13,27 ± 1,85
Lean (Kg) trunk	17,75 ± 2,33	18,13 ± 2,78	17.52 ± 0,10	16,32 ± 1,67	16,10 ± 1,68^d	16,90 ± 1,60	19,29 ± 3,95^c	19,62 ± 4,28^f	18,14 ± 2,79
TBLean (Kg)	36,82 ± 4,66	37,79 ± 5,50	35.80 ± 0.23	34,92 ± 3,27	34,34 ± 3,13	36,46 ± 3,33	40,30 ± 7,47^c	40,90 ± 8,25^f	38,48 ± 5,07
ASMMI (kg/m^2)	6,00 ± 0,54	6,27 ± 0,72	5,61 ± 0,44	6,11 ± 0,47	6,03 ± 0,46	6,30 ± 0,45	6,87 ± 0,91^bc	6,87 ± 0,96^ef	6,85 ± 0,82^t

Carrier (−): G/G −308 TNF-α genotype; carrier (+): A/G −308 TNF-α genotype; BMI: body mass index; WC: waist circumference; HC: hip circumference; PBF: percentage of total body fat mass; TBFat: total body fat mass; TBLean: total body lean mass; ASMMI: appendicular skeletal muscle mass index.
^a𝑃<0.001 NW all versus NWO all; ^b𝑃<0.001 NW all versus PreOB Ob all; ^c𝑃<0.001 NWO all versus Preob-Ob all; ^d𝑃<0.001 NW carrier (−) versus NWO carrier (−); ^e𝑃<0.001 NW carrier (−) versus Preob-Ob carrier (−); ^f𝑃<0.001 NWO carrier (−) versus Preob-Ob carrier (−); ^g𝑃<0.001 NW carrier (+) versus NWO carrier (+); ^h𝑃<0.001 NW carrier (+) versus Preob-Ob carrier (+); ⁱ𝑃<0.001 NWO carrier (+) versus Preob-Ob carrier (+); ^j𝑃<0.001 NW carrier (−) versus NW carrier (+); ^k𝑃<0.001 NWO carrier (−) versus NWO carrier (+); ^l𝑃<0.001 Preob-Ob carrier (−) versus Preob-Ob carrier (+); ^m𝑃<0.05 NW all versus NWO all; ⁿ𝑃<0.05 NW all versus Preob-Ob all; ^o𝑃<0.05 NWO all versus Preob-Ob all; ^p𝑃<0.05 NW carrier (−) versus NWO carrier (−); ^q𝑃<0.05 NW carrier (−) versus Preob-Ob carrier (−); ^r𝑃<0.05 NWO carrier (−) versus Preob-Ob carrier (−); ^s𝑃<0.05 NW carrier (+) versus NWO carrier (+); ^t𝑃<0.05 NW carrier (+) versus Preob-Ob carrier (+); ^u𝑃<0.05 NWO carrier (+) versus Preob-Ob carrier (+); ^v𝑃<0.05 NW carrier (−) versus NW carrier (+); ^w𝑃<0.05 NWO carrier (−) versus NWO carrier (+); ^x𝑃<0.05 Preob-Ob carrier (−) versus Preob-Ob carrier (+).