Functional Polymorphisms of Matrix Metalloproteinases 1 and 9 Genes in Women with Spontaneous Preterm Birth

Table 4

Genotype and allele frequencies of MMP-1-1607 1G/2G and MMP-9-1562 C/T gene polymorphisms in women with SPTB with positive and negative family history of SPTB.

Gene polymorphism	SPTB in family^a; (); (%)	Isolated SPTB; (; (%)	Chi square	value
MMP-1-1607
2G2G	8 (24.2)	15 (20.0)	0.33	0.849
1G2G	18 (54.6)	45 (60.0)
1G1G	7 (21.2)	15 (20.0)
2G	34 (51.5)	75 (50.0)	0.04	0.837
1G	32 (48.5)	75 (50.0)
MMP-9-1562
CC	23 (69.7)	60 (80.0)	1.37	0.242
CT	10 (30.3)	15 (20.0)
TT	0 (0)	0 (0)
C	56 (84.8)	135 (90.0)	1.19	0.276
T	10 (15.2)	15 (10.0)

In mother and/or sibling(s).