Functional Polymorphisms of Matrix Metalloproteinases 1 and 9 Genes in Women with Spontaneous Preterm Birth

Table 7

The association of genotypes and alleles of MMP-1-1607 1G/2G and MMP-9-1562 C/T gene polymorphisms with SPTB depending on gestational age at delivery according to dominant, recessive, and codominant genetic models.

Gene	Genetic model	<33-week SPTB versus 34–37-week SPTB
		OR (95% CI)
MMP-1-1607	Dominant
	1G1G + 1G2G versus 2G2G	0.59 (0.18–1.89)	0.377
	Recessive
	1G1G versus 1G2G + 2G2G	0.81 (0.21–3.12)	0.762
	Codominant
	1G1G versus 2G2G	0.57 (0.12–2.73)	0.481
	1G1G versus 1G2G	0.95 (0.23–3.87)	0.940
	2G2G versus 1G2G	1.67 (0.49–5.62)	0.410
	Alleles
	1G versus 2G	0.77 (0.37–1.61)	0.492
MMP-9-1562	Dominant
	CC + CT versus TT	0.19 (0.00–9.96)	0.412
	Recessive
	CC versus CT + TT	5.73 (0.72–45.57)	0.099
	Codominant
	CC versus TT	0.24 (0.00–12.78)	0.485
	CC versus CT	5.73 (0.72–45.57)	0.099
	TT versus CT	16.33 (0.23–1148.0)	0.198
	Alleles
	C versus T	5.01 (0.65–38.37)	0.121