Fluvastatin Upregulates the α_1C Subunit of CaV1.2 Channel Expression in Vascular Smooth Muscle Cells via RhoA and ERK/p38 MAPK Pathways

Figure 2

Fluvastatin inhibits cell cycle progression as detected by flow cytometry. VSMCs were incubated for 24 hrs with vehicle (a), PDGF (b), or Flu and PDGF (c). Bar graph illustrating the percentage of cells in G0/G1, S, and G2/M phase by the indicated medication (d). Results represented as mean ± SEM of 3 independent experiments in triplicate. versus blank control. versus PDGF stimulated cells. Flu: fluvastatin; PDGF: platelet derived growth factor.

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