Abnormal Expression Pattern of the IL-2 Receptor β-Chain on CD4⁺ T Cells in ANCA-Associated Vasculitis

Figure 2

Gating strategy to determine CD122 expression on CD4⁺CD25^posFoxP3^neg T-helper cells and CD4⁺CD25^posFoxP3^pos regulatory T cells. (a) Representative raw data of a healthy control (HC). Top panels are gated on CD4⁺ T cells, the middle panel is gated on CD25^pos CD4⁺ T cells, and the bottom panels are gated on either FoxP3^posCD25^pos CD4⁺ T cells or FoxP3^negCD25^pos CD4⁺ T cells. (b) Representative raw data of an AAV patient. Top panels are gated on CD4⁺ T cells, the middle panel is gated on CD25^pos CD4⁺ T cells, and the bottom panels are gated on either FoxP3^posCD25^pos CD4⁺ T cells or FoxP3^negCD25^pos CD4⁺ T cells.

(a)

(b)