Transporter TAP1-637G and Immunoproteasome PSMB9-60H Variants Influence the Risk of Developing Vitiligo in the Saudi Population
Table 1
Demographic and clinical features of vitiligo patients ().
Characteristic
Number (%)a
( value)b
Average age (mean ± SD)
At onset (range)
y (2–47 y)
6.0 ()c
(9.3–13.7)
At examination (range)
y (2–50 y)
12.5 ()c
(19.3–24.7)
Ratio of women : men
1 : 1
Family history
34/86 (39.5)
12.3 (<0.0001)
Consanguinity
14/86 (16.3)
4.8 (<0.0001)
Progressive/stabled
48 (66.7)/24 (33.3)
24.0 (<0.0001)
Sensitivity to sun
43/86 (50)
19.1 (<0.0001)
Thyroid pathology (hypo)
14/86 (16.3)
4.8 (<0.0001)
Diabetes mellitus type 1
5/86 (5.8)
0.34 (0.73)
Early graying of hair
24/86 (27.9)
10.3 (<0.0001)
Halo nevie
5/18 (27.8)
10.0 (<0.0001)
Numbers in parentheses are expressed in percentages unless otherwise stated.
bAll values are expressed in terms of -test unless otherwise stated.
cValues are expressed in terms of -test.
d14 cases could not be clinically followed up.
eOnly 18 of 86 cases were investigated for halo nevi.
