Research Article
High Nuclear Expression of HDGF Correlates with Disease Progression and Poor Prognosis in Human Endometrial Carcinoma
Table 2
Summary of univariate and multivariate Cox regression analysis of overall survival duration.
| Parameter | Univariate analysis | Multivariate analysis | | HR | 95% CI | | HR | 95% CI |
| Age | | | | | | | <50 versus ≧50 | 0.093 | 0.401 | 0.138–1.165 | | | | Family history of tumor | | | | | | | Negative versus positive | 0.279 | 0.325 | 0.043–2.487 | | | | Education | | | | | | | <Graduation versus ≧graduation | 0.298 | 26.921 | 0.055–13271.753 | | | | Health Insurance | | | | | | | No versus yes | 0.089 | 0.020 | 0.000–1.811 | | | | Career | | | | | | | ≦Worker versus >worker | 0.272 | 27.978 | 0.073–10713.674 | | | | Menopausal status | | | | | | | Premenopausal versus postmenopausal | 0.559 | 0.721 | 0.240–2.160 | | | | Complications | | | | | | | With versus without | 0.125 | 0.309 | 0.069–1.384 | | | | FIGO stage | | | | | | | I + II versus III | 0.002 | 5.652 | 1.892–16.883 | 0.729 | 1.392 | 0.215–9.006 | Histological grading | | | | | | | G1 versus G2 versus G3 | 0.001 | 4.514 | 1.896–10.745 | 0.097 | 2.170 | 0.870–5.412 | Lymph node status | | | | | | | Negative versus positive | ≤0.001 | 12.232 | 4.196–35.659 | 0.070 | 5.543 | 0.872–35.231 | Depth of myometrial invasion | | | | | | | <50% versus ≧50% | ≤0.001 | 9.745 | 2.713–34.999 | 0.090 | 3.673 | 0.818–16.498 | HDGF expression | | | | | | | Low expression versus high expression | 0.004 | 4.951 | 1.686–14.544 | 0.111 | 2.828 | 0.787–10.165 | Postoperative irradiation | | | | | | | Yes versus no | 0.512 | 1.652 | 0.368–7.409 | | | | Postoperative chemotherapy | | | | | | | Yes versus no | 0.175 | 2.081 | 0.721–6.005 | | | | Postoperative hormone therapy | | | | | | | Yes versus no | 0.044 | 0.267 | 0.074–0.963 | 0.703 | 0.748 | 0.169–3.322 |
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