The Association between Bile Salt Export Pump Single-Nucleotide Polymorphisms and Primary Biliary Cirrhosis Susceptibility and Ursodeoxycholic Acid Response
Table 5
The association between BSEP SNPs and UDCA response.
SNP
UDCA CR (%)
UDCA NR (%)
Adjusted* OR (95% CI)
value
rs52304393
CC + CT
28 (0.44)
13 (0.41)
1.34 (0.21–0.99)
0.58
TT
36 (0.56)
19 (0.59)
1.00
rs473351
AA + AG
14 (0.22)
6 (0.20)
1.63 (1.01–4.87)
0.90
GG
50 (0.78)
26 (0.80)
1.00
rs860510
TT + TG
40 (0.62)
18 (0.57)
1.32 (1.03–2.38)
0.22
GG
24 (0.38)
14 (0.43)
1.00
rs2287618
AA + AG
38 (0.60)
14 (0.43)
0.32 (0.25–0.65)
0.01
GG
26 (0.40)
18 (0.57)
1.00
By age and sex adjustment and analyzed by logistic regression analyses.