Prognostic and Biological Significance of MicroRNA-127 Expression in Human Breast Cancer

Table 2

Univariate and multivariate analysis for OS of BC patients.

Variables	Univariate analysis		Multivariate analysis
	RR (95% CI)	P value	RR (95% CI)	P value
Age (year)	0.665 (0.342–1.212)	0.104
Tumor size (cm)	0.882 (0.602–1.018)	0.318
Differentiation grade	0.912 (0.708–2.023)	0.175
ER status	0.559 (0.512–1.022)	0.084
PR status	0.912 (0.833–1.642)	0.322
HER-2 status	2.921 (1.456–2.873)		0.598 (0.423–0.977)	0.118
Lymph node metastasis	1.877 (1.228–3.702)		2.097 (1.005–2.506)
Clinical stage	2.538 (1.318–2.808)		1.676 (1.278–3.121)
miR-127 expression	1.798 (1.333–2.552)		2.023 (1.437–2.855)

P 0.05. HR: hazard ratio; 95% CI: 95% confidence interval.