Assessment of Urinary Osteopontin in Association with Podocyte for Early Predication of Nephropathy in Diabetic Patients
Table 2
The levels of urinary immunoglobulin M, osteopontin, and podocyte in all studied groups (mean ± SD).
Parameters
Patients groups
Normal control
Diabetic (normoalbuminuria)
Diabetic (microalbuminuria)
Nephrotic diseases
IgM (ng/L)
Mean ± SD
2.1 ± 0.06
3 ± 0.3
31.7 ± 2.8
26.3 ± 2.2
value
—
N.S
<0.001
<0.001
value
—
—
<0.001
N.S
Osteopontin (U/L)
Mean ± SD
120.8 ± 23
130 ± 56
312.7 ± 25.8
179.3 ± 28.2
value
—
N.S
<0.001
<0.01
value
—
—
<0.001
<0.001
Podocyte (cells/mL)
Mean ± SD
Nil
Nil
3.9 ± 0.07
2.3 ± 0.2
value
—
—
—
<0.001
value
—
—
—
<0.01
= number of cases. value: diabetic normoalbuminuria and nephritic syndrome versus control. value: diabetic microalbuminuria versus diabetic normoalbuminuria.