A Disease Modification Effect of APOE E4 on the Association between Urinary Albumin Excretion and Cognition in Korean Adults
Table 2
Demographics of participants according to APOE E4 status.
E4 noncarrier
E4 carrier
Number (%)
8492 (83.3%)
1698 (16.7%)
Age, y
61.6 ± 7.8
61.5 ± 7.7
0.494
Women, %
60.4
62.0
0.220
Formal education, (%)
None
34.8
34.5
0.839
1~6 years
40.3
40.4
More than 9 years
24.9
25.1
CES-DK
52.1 ± 8.6
52.5 ± 8.4
0.139
Current smoker, %
15.4
14.7
0.432
Current drinker, %
47.6
46.4
0.369
Hypertension, %
40.0
39.3
0.574
Type 2 diabetes, %
13.5
13.1
0.656
Hyperlipidemia, %
10.2
13.0
0.001
Body mass index, kg/m2
24.4 ± 3.1
24.4 ± 3.1
0.756
Systolic blood pressure, mmHg
126.1 ± 18.3
125.7 ± 18.4
0.415
Diastolic blood pressure, mmHg
80.5 ± 10.2
80.3 ± 10.1
0.543
Fasting blood glucose, mg/dL
104.9 ± 24.0
104.0 ± 23.4
0.148
UACR, mg/g
44.7 ± 146.7
43.0 ± 161.6
0.654
eGFR*, µmol/L
77.7 ± 14.6
78.4 ± 14.5
0.049
Data are expressed as mean ± SD or percentages. CES-D-K: the Center for Epidemiological Study-Depression Scale Korean version, UACR: urinary albumin-to-creatinine ratio, and eGFR: estimated glomerular filtration rate. *eGFR was calculated with the 4-variable modification of diet in renal disease (MDRD) formula. values are shown for chi-square tests and -tests, as appropriate.
