Clinical Study
A Comparison of KL-6 and Clara Cell Protein as Markers for Predicting Bronchopulmonary Dysplasia in Preterm Infants
Table 1
Comparison of demographic and clinical characteristics between infants with and without BPD
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| | BPD | Without BPD | P value |
| Number of patients | 24 | 49 | | Birth weight, g | 1124.6 ± 216.8 | 1311.8 ± 115.6 | <0.0001 |
| Gestational age, weeks | 29.2 ± 1.7 | 31.2 ± 1.0 | 0.07 | Male | 15 (62.5%) | 22 (44.9%) | 0.16 |
| Apgar score at 1 min | 5.5 3.5–7 | 7 5–7 | 0.14 | Apgar score at 5 min | 6 5–8 | 7 7-8 | 0.10 |
| Apgar score at 10 min | 7 7-8 | 8 [8-8 | 0.07 | Vaginal delivery | 7 (29.2%) | 9 (18.4%) | 0.3 |
| Prenatal steroids | 23 (95.8%) | 44 (89.8%) | 0.39 | Maternal pregnancy-induced hypertension | 7 (29.2%) | 18 (36.7%) | 0.52 |
| Maternal diabetes | 2 (8.3%) | 1 (2.0%) | 0.24 | Maternal infection | 2 (8.3%) | 4 (8.2%) | 0.98 |
| Premature rupture of membranes | 11 (45.8%) | 13 (26.5%) | 0.1 | Cord blood pH | 7.30 ± 0.08 | 7.30 ± 0.08 | 1.0 |
| Ureaplasma urealyticum positive in urine | 3 (12.5%) | 12 (13.3%) | 0.56 | Surfactant use | 23 (95.8%) | 31 (34.4%) | 0.03 |
| Mechanical ventilation ≥1 week | 11 (45.8%) | 4 (8.2%) | 0.003 | Pneumonia | 4 (16.7%) | 3 (6.1%) | 0.17 |
| Sepsis | 18 (75.0%) | 22 (44.9%) | 0.02 | Sepsis occurred within 15 days after birth | 16 (66.7%) | 14 (28.6%) | 0.003 | Sepsis occurred after 15 days after birth | 2 (8.3%) | 8 (16.3%) | 0.36 | Patent ductus arteriosus | 6 (25.0%) | 4 (8.2%) | 0.06 |
| Length of stay, d | 49.9 ± 11.2 | 40.3 ± 6.6 | 0.0001 | Patients discharged alive | 20 (83.3%) | 49 (100.0%) | 0.04 |
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Values are expressed as median [range] or number of individuals (percentage).
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