Disease Markers

Research Article

Individually Tailored Screening of Susceptibility to Sarcopenia Using p53 Codon 72 Polymorphism, Phenotypes, and Conventional Risk Factors

Table 2

Anthropometric and body composition (DXA) parameters according to p53 codon 72 polymorphism genotypes.


	NWO			NW			Preob-Ob
	All ( = 39)	Arg/Arg genotype ( = 18)	Carriers of *proallele ( = 21)	All ( = 18)	Arg/Arg genotype ( = 10)	Carriers of *proallele ( = 8)	All ( = 70)	Arg/Arg genotype ( = 39)	Carriers of *proallele ( = 31)

Height (cm)	161,00 ± 0,88	162,50 ± 0,94	161,00 ± 1,42	165,00 ± 1,10^a	164,50 ± 1,33	165,25 ± 1,94	161,00 ± 0,64^c	161,00 ± 0,78^m	162,00 ± 1,09
Weight (Kg)	58,50 ± 0,86	56,10 ± 1,22	58,80 ± 1,20	54,25 ± 0,99^a	56,10 ± 1,00	52,00 ± 1,60^e,h	87,05 ± 2,52^b,c	84,00 ± 3,06^i,m	95,00 ± 4,13^l,n
BMI (Kg/m²)	22,24 ± 0,26	21,67 ± 0,40	23,10 ± 0,30^d	20,60 ± 0,34^a	21,03 ± 0,27	19,04 ± 0,62^h	32,98 ± 0,96^b,c	30,74 ± 1,23^i,m	33,78 ± 1,50^l,n
WC (cm)	72,50 ± 1,15	72,00 ± 0,97	73,75 ± 1,88	66,00 ± 1,12^a	71,00 ± 1,45	65,00 ± 1,60^h	95,25 ± 2,25^b,c	94,50 ± 2,68^i,m	101,00 ± 3,74^l,n
HC (cm)	97,50 ± 1,03	96,50 ± 1,31	97,50 ± 1,57	91,00 ± 1,85^a	95,00 ± 1,22	90,50 ± 3,47^h	115,00 ± 1,79^b,c	113,50 ± 2,23^i,m	117,00 ± 2,92^l,n
W/H	0,73 ± 0,01	0,72 ± 0,01	0,76 ± 0,01^d	0,74 ± 0,02	0,74 ± 0,01	0,73 ± 0,04	0,82 ± 0,01^b,c	0,81 ± 0,01^i,m	0,83 ± 0,02^l,n
PBF (%)	34,40 ± 0,62	33,35 ± 1,02	35,60 ± 0,78	25,10 ± 0,75^a	26,00 ± 0,84^g	24,10 ± 1,28^h	47,80 ± 0,64^b,c	46,20 ± 0,84^i,m	48,60 ± 1,00^l,n
TBF (Kg)	20,02 ± 0,82	19,06 ± 1,20	21,37 ± 1,12	13,65 ± 0,60^a	14,32 ± 0,62^g	11,82 ± 1,04^h	38,07 ± 1,71^b,c	36,73 ± 2,04^i,m	44,04 ± 2,89^l,n
Lean arms (Kg)	3,43 ± 0,13	3,42 ± 0,23	3,60 ± 0,13	2,68 ± 0,22	3,81 ± 0,28	2,07 ± 0,29^h	4,07 ± 0,15^b,c	3,93 ± 0,20ⁱ	4,36 ± 0,21^l,n
Lean legs (Kg)	11,91 ± 0,35	11,79 ± 0,27	12,07 ± 0,61	12,82 ± 0,25^a	13,07 ± 0,36^g	12,30 ± 0,32	14,63 ± 0,34^b,c	14,11 ± 0,47ⁱ	14,99 ± 0,45^l,n
TBL (Kg)	34,92 ± 0,48	34,79 ± 0,63	34,92 ± 0,73	37,81 ± 0,58^a	38,15 ± 0,73^g	36,56 ± 0,77^e	43,32 ± 0,90^b,c	42,33 ± 1,09ⁱ	45,67 ± 1,48^l,n
RMR (Kcal)	1294,00 ± 17,83	1289,00 ± 23,20	1294,00 ± 27,01	1401,00 ± 21,58^a	1413,50 ± 27,20^g	1355,00 ± 28,33^e	1605,00 ± 33,42^b,c	1569,00 ± 40,37ⁱ	1692,00 ± 54,97^l,n
ASMMI (kg/m²)	5,93 ± 0,14	5,83 ± 0,15	5,94 ± 0,24	5,79 ± 0,13	5,94 ± 0,16	5,38 ± 0,17^e	7,10 ± 0,15^b,c	6,96 ± 0,22^i,m	7,30 ± 0,19^f,n

BMI: body mass index; WC: waist circumference; HC: hip circumference; PBF: percentage of total body fat mass; TBFat: total body fat mass; TBLean: total body lean mass; RMR: resting metabolic rate; ASMMI: appendicular skeletal muscle mass index.
^a ≤ 0,05 NWO all versus NW all; ^b ≤ 0,05 NWO all versus Preob-Ob all; ^c ≤ 0,05 NW all versus Preob-Ob all; ^d ≤ 0,05 NWO *Arg/*Arg genotype versus NWO carriers of *proallele; ^e ≤ 0,05 NW *Arg/*Arg genotype versus NW carriers of *proallele; ^f ≤ 0,05 Preob-Ob *Arg/*Arg genotype versus Preob-Ob carriers of *proallele; ^g ≤ 0,05 NWO C*Arg/*Arg genotype versus NW *Arg/*Arg genotype; ^h ≤ 0,05 NWO carriers of *proallele versus NW carriers of *proallele; ⁱ ≤ 0,05 NWO C*Arg/*Arg genotype versus Preob-Ob *Arg/*Arg genotype; ^l ≤ 0,05 NWO carriers of *proallele versus Preob-Ob carriers of *proallele; ^m ≤ 0,05 NW *Arg/*Arg genotype versus Preob-Ob *Arg/*Arg genotype; ⁿ ≤ 0,05 NW carriers of *proallele versus Preob-Ob carriers of *proallele.