Impact of Serum Biomarkers and Clinical Factors on Intensive Care Unit Mortality and 6-Month Outcome in Relatively Healthy Patients with Severe Pneumonia and Acute Respiratory Distress Syndrome
Table 1
Clinical factors characteristics between ICU survivors and nonsurvivors.
ICU survivors (n = 40)
ICU nonsurvivors (n = 16)
P
Age
63.43 ± 13.95
70.63 ± 9.22
0.063
Sex, male
23
8
0.767
Pneumonia type
0.262
Community acquired
23
7
Hospital acquired
17
9
Initial PaO2/FiO2
163.05 ± 60.68
160.57 ± 58.24
0.889
Charlson’s comorbidity index
2.03 ± 1.31
2.62 ± 1.31
0.127
Initial antibiotics
<0.001
Appropriate
17
0
Inappropriate
8
13
Indeterminate
15
3
APACHE II score
Day 1
25.47 ± 5.29
29.37 ± 5.02
0.015
Day 3
22.45 ± 5.90
30.50 ± 6.59
<0.001
Day 3 : Day 1
0.88 ± 0.11
1.04 ± 0.15
0.001
SOFA score
Day 1
8.27 ± 2.62
11.38 ± 2.82
<0.001
Day 3
7.53 ± 2.35
11.37 ± 2.63
<0.001
Day 3 : Day 1
0.93 ± 0.21
1.03 ± 0.23
0.147
SAPS II score
Day 1
41.05 ± 9.12
49.50 ± 11.55
0.005
Day 3
37.70 ± 8.27
50.44 ± 13.39
<0.001
Day 3 : Day 1
0.92 ± 1.01
1.02 ± 0.12
0.003
Continuous variables were analyzed by Student’s t-test or Mann-Whitney U test, and categorical data by Chi-square test.
bICU: intensive care unit; APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment; and SAPS II: Simplified Acute Physiology Score II.
cVariables are expressed as mean (standard deviation) and categorical data are expressed as number (percentage).
