Impact of Serum Biomarkers and Clinical Factors on Intensive Care Unit Mortality and 6-Month Outcome in Relatively Healthy Patients with Severe Pneumonia and Acute Respiratory Distress Syndrome
Table 3
Clinical characteristics of 6-month life-independent and life-dependent patients.
6-month life independence (n = 25)
6-month life dependence (n = 10)
P
Age
57.12 ± 12.51
75.30 ± 8.07
<0.001
Sex, male
16
5
0.474
Pneumonia type
0.002
Community acquired
20
2
Hospital acquired
5
8
Initial PaO2/FiO2
173.13 ± 63.84
135.76 ± 56.83
0.117
Charlson’s Comorbidity Index
1.64 ± 1.15
3.20 ± 1.13
0.001
Initial antibiotics
1.000
Appropriate
10
4
Inappropriate
5
2
Indeterminate
10
4
APACHE II score
Day 1
24.72 ± 5.22
25.80 ± 1.64
0.584
Day 3
21.04 ± 4.63
23.30 ± 5.37
0.221
Day 3 : Day 1
0.85 ± 0.11
0.91 ± 0.11
0.209
SOFA score
Day 1
8.00 ± 2.75
8.20 ± 1.69
0.833
Day 3
7.52 ± 2.42
6.80 ± 2.10
0.416
Day 3 : Day 1
0.96 ± 0.20
0.82 ± 0.13
0.044
SAPS II score
Day 1
39.24 ± 7.17
43.90 ± 12.92
0.181
Day 3
36.36 ± 7.92
39.60 ± 10.29
0.323
Day 3 : Day 1
0.93 ± 0.09
0.91 ± 0.09
0.759
ICU stay
17.68 ± 8.57
27.00 ± 8.56
0.007
Hospital stay
32.80 ± 16.79
61.20 ± 19.20
<0.001
MV day
15.24 ± 8.04
23.30 ± 7.62
0.010
Continuous variables were analyzed by Student’s t-test or Mann-Whitney U test, and categorical data by Chi-square test.
bICU: intensive care unit; APACHE II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment; SAPS II: Simplified Acute Physiology Score II; MV: mechanical ventilation.
cVariables are expressed as mean (standard deviation) and categorical data are expressed as number (percentage).
